Pregabalin CAS NO.148553-50-8

Pregabalin is a chemical compound with the molecular formula C8H17NO2. It is a medication that falls under the class of anticonvulsant drugs. Pregabalin is a derivative of gamma-aminobutyric acid (GABA), a neurotransmitter in the central nervous system. Structurally, it is related to the inhibitory neurotransmitter GABA, but its mechanism of action is different. In terms of physical properties, pregabalin is a white crystalline solid. Its solubility characteristics include being practically insoluble in water and freely soluble in polar organic solvents. Pregabalin is available in oral dosage forms, such as capsules or tablets, for medicinal use. 

Pregabalin is commonly used to treat various medical conditions, including neuropathic pain, fibromyalgia, and certain types of seizures. It exerts its therapeutic effects by binding to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding modulates the influx of calcium ions, reducing the release of neurotransmitters, and thereby decreasing the excitability of nerve cells.

Synonyms

(3S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID; (R)-Pregabalin; (S)-(+)-3-aminomethyl-5-methylhexanoic acid; (S)-3-(Aminomethyl)-5-methylhexanoic acid; (S)-3-(Aminomethyl)-5-methylhexanoic acid CI-1008 PD-144723;